A comparison of PSA level, lipid profile, indices of central obesity, glucose level, and insulin level in treatment-naïve patients with CaP, patients treated with ADT for up to 1 year, and patients treated with ADT for more than 1 year showed significant variations in mean values of PSA (P < .001), LDL cholesterol (P = .043), and BMI (P = .003). Here, KLK3 is linked to Abdominal obesity.