A comparison of PSA level, lipid profile, indices of central obesity, glucose level, and insulin level in treatment-naïve patients with CaP and ADT-treated patients with CaP and controls showed significant variations in mean values of PSA (P < .001), total cholesterol (P = .016), waist circumference (P = .050), and BMI (P = .003) among the groups. Here, KLK3 is linked to Abdominal obesity.