ALMS1 and ciliopathy: We suggest that extreme caution should be exercised in assigning pathogenicity to ALMS1 missense variants, and, given the overlap in clinical features among different ciliopathies, that wider analysis of a ciliopathy gene panel is warranted in any patient with features thought to denote Alström syndrome but without two convincing loss‐of‐function ALMS1 mutations, especially where the phenotype is atypical or mild.