Thus signaling cascade of circRNA_021412/miR-1972/LPIN1 induced the expression of 8 steatosis-related genes, including ACSL1, ACSL3, ACSL4, ACSL6, ACSS2, G6PC, ME1, and SCP2 (Figure 5(b)), via PPARα activation [36]. This evidence concerns the gene ME1 and steatosis.