In addition, inflammatory cytokines such as interferon-γ (IFN-γ), tumor necrosis factor-α, and interleukin-1 release due to intensive WL and massive lipolysis probably are involved in the incidence of MS.3,4 Our observations buttressed earlier studies suggesting that neurological adverse effects have been observed after severe WL in obese people.4 This evidence concerns the gene IFNG and myeloid sarcoma.