In addition, angiogenesis is the basis of tumor growth, metastasis, invasion and recidivism, and the results of the CAM model confirmed that the tumorigenic and angiogenic ability of NSCLC cells was weakened after silencing the expression of HOXA11-AS, indicating that HOXA11-AS has a promoting effect on angiogenesis. This evidence concerns the gene HOXA11 and neoplasm.