In addition, HPV16 E6 promoted EMT and invasion in cervical cancer via the repression of miR-218, while miR-218 inhibited EMT and invasion in cervical cancer by targeting Scm-like with four MBT domains 1 (SFMBT1) and defective in cullin neddylation 1, domain containing 1 (DCUN1D1)33. This evidence concerns the gene DCUN1D1 and cervical carcinoma.