To investigate the role of neuropilin-1 (Nrp1) in the TME, Abigail E. Overacre-Delgoffe (University of Pittsburgh) utilized a model of melanoma in Nrp1L/LFoxP3Cre-YFP/DTR-GFP mice in which regulatory T cells (Treg) are either wild-type (WT; 50%) or Nrp1-deficient (50%). Here, NRP1 is linked to melanoma.