To evaluate the relationship between GSK‐3β activity index and chronic inflammation in CRSsNP, we detected the mRNA expression of inflammation‐related genes (T‐bet, RORC, GATA3, IFN‐γ, IL‐4, IL‐5, IL‐13, and IL‐17A). Here, IL17A is linked to chronic rhinosinusitis without nasal polyps.