In a recent study on CRSwNP, the positive correlation was found among the expression of GSK‐3β, PI3K/Akt and IL‐6 in CRSwNP, which suggested that GSK‐3β may play a pro‐inflammatory role in the occurrence and development of CRSwNP 21. This evidence concerns the gene GSK3B and chronic rhinosinusitis with nasal polyps.