It was reported that p21-activated protein kinase 1 induced the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2, and FADD protected pancreatic cancer cells from drug-induced apoptosis (Li et al., 2017; Zhang et al., 2017). The gene discussed is FADD; the disease is familial pancreatic carcinoma.