EYA1 and neoplasm: As is shown in Figure 2a and 2b, despite the relationship between EYA1 content and neural crest tumor major differentiation class, among neuroblastomas, there was no statistically significant difference in EYA1 protein level between tumors with favourable or unfavourable histology, or between tumors with low or intermediate MKI (i.e., ≤ 4%) and those with high MKI.