In addition, the lncRNA breast cancer anti-estrogen resistance 4 (BCAR4), functioning in breast cancer metastasis, was discovered to directly interact with Smad nuclear-interacting protein 1 (SNIP1) and Serine/threonine-protein phosphatase one regulatory subunit 10 (PPP1R10 or PNUTS), thus activating phosphor-GLI2 dependent gene expression (Xing et al., 2014). This evidence concerns the gene GLI2 and breast carcinoma.