All these genes are associated with psychiatric conditions, ranging from ID i.e., CNKSR2 (Kessels and Malinow, 2009; Vaags et al., 2014), CTNNB1 (Tucci et al., 2014), ANK3 (Iqbal et al., 2013), CASK (Tarpey et al., 2009) and ASD i.e., CTNND2 (Turner et al., 2015), ANK3 (Iqbal et al., 2013) to schizophrenia i.e., CNKSR2 (GWAS, PGC-SCZ 2014) and bipolar disorder ANK3 (Ferreira et al., 2008). This evidence concerns the gene CASK and bipolar disorder.