Postischemia administration of 2.7 g/Kg/day XFZYD also significantly [I/R + XFZYD2.7 (VEGF = 1.90 ± 0.34; HIF-1α = 1.87 ± 0.22; PKM2 = 5.86 ± 0.95, p < 0.001; RBP2 = 5.19 ± 1.17, p = 0.008)] mitigated this ischemia-induced increase. This evidence concerns the gene HIF1A and ischemia.