As shown in Fig. 6a and b, 62.7% (32 cases) of thyroid cancer samples with high Trop2 expression (51 cases) exhibited high levels of MMP2, whereas 64.4% (29 cases) of samples with low Trop2 expression (45 cases) showed low levels of MMP2 (p < 0.05) (Spearman rho = 0.276, P = 0.007). This evidence concerns the gene TACSTD2 and thyroid cancer.