IL2 and systemic lupus erythematosus: To this end, the use of recombinant interleukin 2 (rIL-2) has been beneficial as several successes of low-dose rIL-2 therapy in animal models of autoimmune pathology [10–14] and human clinical studies in hepatitis C virus induced vasculitis, chronic graft-versus-host disease (GVHD), Type1 Diabetes (T1D), systemic lupus erythematosus (SLE), and Alopecia areata [15–21] have been reported.