Both Hsp90 (HSP90AA1; heat shock protein 90 kDa α (cytosolic), class A member 1) and Hsp110 (HSPH1; heat shock 105 kDa/110 kDa protein 1) were markedly reduced in miR-27a mimic-transfected oral cancer HSC-4 cells [107]. This evidence concerns the gene HSPH1 and lip and oral cavity carcinoma.