This disease association is particularly interesting as patients with compound heterozygous TBC1D24 mutations can also present with hearing loss associated with an early-onset epileptic encephalopathy (Stražišar 2015); furthermore, dominant (Azaiez et al. 2014; Zhang et al. 2014) and recessive (Rehman Atteeq et al. 2014) TBC1D24 mutations can also cause non-syndromic hearing impairment, with no reported epileptic phenotype (Azaiez et al. 2014; Rehman Atteeq et al. 2014; Zhang et al. 2014). This evidence concerns the gene TBC1D24 and Epileptic encephalopathy.