A more recent study has highlighted the importance of distinguishing these NCOA7 isoforms; in peripheral blood mononuclear cells from multiple sclerosis patients treated with IFNβ1b, a unique short NCOA7 isoform was significantly induced by more than 60-fold only 4 h post-IFNβ1b treatment (Yu et al. 2015). Here, NCOA7 is linked to multiple sclerosis.