Activation of NK cells by cytokine trans-presentation, mainly IL-15, has been previously reported (Lucas et al., 2007; Mortier et al., 2008; Bihl et al., 2010; Zanoni et al., 2013) and cannot be ruled out as a possible mechanism in the context of GBS or S. suis infection. Here, IL15 is linked to Guillain-Barre syndrome.