Others observed that serum levels of miR-22, miR-375, and miR-451 were increased in patients with HT compared with healthy subjects and that serum levels of miR-16, miR-22, miR-375, and miR-451 were increased in patients with GD (40), while another study revealed significant variations of miR-200a and miR-155 in purified CD4+ T-cells and CD8+ T-cells of patients suffering from GD and HT (41). The gene discussed is CD8A; the disease is hematocrit.