Nevertheless, specific canonical pathways unique to either compound were also found, for example, adenine and adenosine salvage VI and spermidine biosynthesis I specific for DET treatment, and role of interleukin 17A (IL-17A) in psoriasis, liver X receptor/retinoid X receptor (LXR/RXR) activation, and calcium transport I specific for DETD-35 treatment (Figure 6A). The gene discussed is IL17A; the disease is psoriasis.