Behavioral and metabolic disorders might share common developmental pathways and impinge upon common mediators, including glucocorticoids (GC)—the main adrenocortical stress hormones—and neurotrophins (most notably brain-derived neurotrophic factor—BDNF), both of which are involved in brain plasticity and metabolic regulation (Tamashiro and Moran, 2010; Lee et al., 2014; Mansur et al., 2015). The gene discussed is BDNF; the disease is Other metabolic disease.