FLVCR1 and type 2 diabetes mellitus: Considering these intriguing studies17–27 and the importance of FLVCR1 in the maintenance of tissue heme homeostasis12–16, we aimed to investigate cross-sectionally (in two cohorts) the expression of FLVCR1 according to obesity and type 2 diabetes (T2D), and longitudinally the effects of weight gain (in rats) and weight loss (bariatric surgery of morbidly obese subjects) on AT FLVCR1 mRNA levels.