Even though we did not find any significantly differentially regulated genes in liver tissue, Prkaa, Hmgcr, Acat, Ldlr, Lpl, Slc27a2, Acot3, Ppara, and Ppargc1 showed inverse correlation with plasma triglyceride in WD + PDX while in WD there was no correlation (Supplementary Table S2). Here, ACAT1 is linked to Wilson disease.