EGF and early-onset autosomal dominant Alzheimer disease: The angiogenic, Alzheimer disease-presenilin pathway, EGF/FGF/gonadotrophin signalling, inflammation mediated by chemokine and cytokine signalling with PDGF/Notch/vascular epidermal growth factor (VEGF) and Wnt signalling pathways were a few of which had the greatest number of entities related.