Cancer-associated modifications of chromatin remodelers such as SNF5 (part of the subunit of the SWI/SNF chromatin remodeling complex), Brahma-related gene-1 (BRG1), and MTA family members (Metastasis-associated gene), are frequently found mutated in malignancies, suggesting a tumor suppressor role [58,59,60]. Here, SMARCA1 is linked to neoplasm.