LGALS9 and pulmonary emphysema: Differential cell analyses showed that the numbers of neutrophils and lymphocytes markedly increased on day 7, and the exogenous administration of Gal-9 in the PPE-induced emphysema model resulted in a striking decrease in the number of total cells, neutrophils, and lymphocytes, with a 54.5%, 74.3%, and 78.2% reduction, respectively, compared to controls (Fig 2A, 2B and 2D).