As shown in Fig 2, PMPs promoted the adhesion of RA-FLSs onto collagen I, fibronectin and matrigel, the statistically significance was shown in the group of 50 μg/ml PMPs, indicating that PMPs might play a positive regulatory role in the adhesion of RA-FLSs to ECM. The gene discussed is FN1; the disease is rheumatoid arthritis.