Two SNPs, rs2105450 (AKR1C3, prostaglandin F synthase) and rs4792147 (ALOX15B, arachidonate 15-lipoxygenase, type B) had significant SNP-sex interactions with p-values < 0.05 (Table 4), but neither of these SNPs were significantly associated with NSCLC survival in multivariable models among men and women. This evidence concerns the gene ALOX15B and non-small cell lung carcinoma.