Interestingly, several genes (Adcyap1, Cntnap2, Grid1, Nrxn1, Nrxn3, Ucn, Tbx1, and Nr2e1), that are associated with disorders [32, 33], stress response [34], social behaviors [35–37] or autism spectrum disorders [38–42], are up-regulated specifically in the hippocampus of Del/+ mice. The gene discussed is NRXN3; the disease is autism spectrum disorder.