As EGFR has been shown to promote cancer cell proliferation, migration, and invasion as well as epithelial-to-mesenchymal transition (EMT), a process important for cell migration and invasion,25, 26 and EGFR regulates the miR-338-3p/EYA2 axis, we investigated whether EGFR regulates these effects through the miR-338-3p/EYA2 pathway. The gene discussed is EGFR; the disease is cancer.