Consistently, the protein levels of these cytokines/chemokines in supernatants were also markedly increased (e.g., up to 80-fold greater for IL8) as measured by multiple human cytokines assays (Figure 2b), indicating robust production of cytokine proteins by breast cancer cells themselves after exposure to chemotherapeutics followed by drug withdrawal. The gene discussed is CXCL8; the disease is breast carcinoma.