CXCR4 and breast neoplasm: CXCR4 is a receptor for chemokine CXCL12 and its aberrant overexpression has been implicated in BCSCs and breast tumor metastasis.29, 30, 31, 32 Mechanically, the current study reported that BAG3 stabilized CXCR4 mRNA via interaction with its coding region (CR) and 3′-untranslational region (3′UTR).