Analysis of cytokine protein expression from supernatant cultures, taken at the exponential growth phase of both MM cell lines, at comparable cell numbers, indicated a significant increase in the expression levels of monocyte/leukocyte chemoattractant CXCL-10 and MIP-1β chemokines in RPMI 8226 cell line as compared to L363 cell line (Figure 3). This evidence concerns the gene CCL4 and Miyoshi myopathy.