Abuannadi et al. compared 40 patients with hyperglycemia (30 with diabetes on oral agents or basal insulin before admission) who received exenatide infusion to historical controls on an insulin infusion protocol with target glucose of 90-119 mg/dl (intensive control era-INT) and 100–140 mg/dl (moderate control era-MOD) [47]. This evidence concerns the gene INS and diabetes mellitus.