TNF and ischemic stroke: To search for possible molecular functions we made a combined miRPath [44] (version 3.0) analysis of the up-regulated miR-9-3p, miR-9-5p, miR-107, miR-124-3p, and miR-128-3p (results merged by genes union, FDR correction, P < 0.05) which identified several KEGG pathways relevant to ischemic stroke, including pathways involved in p53 signaling, cell cycling, tumor necrosis factor (TNF) signaling, hypoxia inducible factor 1 (HIF-1) signaling and neurotrophin signaling.