TRAF1 and autoimmune thrombocytopenic purpura: After adjusting for age and gender, ITP patients carrying the AG genotype of TRAF1 rs10818488 showed a 1.713-fold increased risk of developing severe ITP compared with patients carrying major genotype GG under codominant model (OR = 1.713, 95% CI = 1.008–2.911, p = 0.047).