In addition, genetic variants of a cluster of inflammation-related genes, including CD24, CD226, FCRL3, IL2, IRF5, ITGAM, NLRP3, CARD8, PTPN22, SH2B3, STAT4, TNFAIP3, and TRAF1, are associated with diverse autoimmune diseases. Here, TNFAIP3 is linked to autoimmune disease.