HF biomarkers can be broadly grouped into markers of inflammation (e.g., C-reactive protein, myeloperoxidase), markers of fibrosis and extracellular remodeling (e.g., procollagen, galectin-3, ST2), markers of mechanical strain (e.g., natriuretic peptides), markers of hemodynamic homeostasis (e.g., copeptin, adrenomedullin), and markers of cardiomyocyte injury (e.g., troponins) [6, 50]. Here, LGALS3 is linked to hydrops fetalis.