REN and hyperuricemia: Unpublished observations presented by Vincent Morinière and colleagues at the 43rd Annual Meeting and Scientific Exposition of the American Society of Nephrology in 2010 include discovery of the same p.(Trp17Arg) REN mutation in an individual with chronic tubulointerstitial nephritis and hyperuricaemia with a family history of both tubulointerstitial kidney disease and gout, providing further evidence for the pathogenicity of this variant.