No association was observed between genetic score for adult BMI and WHR for total and aggressive prostate cancer (defined as a Gleason score of ≥ 8, a disease stage of ‘distant’, a PSA level of > 100 ng/mL or death from prostate cancer); however, associations were not examined separately by tumour stage and grade [33]. The gene discussed is KLK3; the disease is Familial prostate cancer.