CD40LG and Epstein-Barr virus infection: This study aimed to compare cytomegalovirus (CMV) and Epstein–Barr virus (EBV) reactivations (based on viremias) between young and elderly women who had a chronic CMV and/or EBV infection (i.e., an IgG+ serostatus) without an acute infection (i.e., an IgM− serostatus), and among the elderly group categorized according to frailty status.