BSG and carcinoma: A random-effects model showed that CD147 expression was higher in esophageal cancer tissues (71.29%) than in para-carcinoma tissues (17.63%) (OR = 12.80, 95% CI = (6.57, 24.92), p < 0.00001) with significant heterogeneity (p < 0.0001, I2 = 75%) (Fig 3C).