BSG and esophageal cancer: With significant heterogeneity (p < 0.00001, I2 = 77%), a random-effects model showed that CD147 expression in esophageal cancer (72.83%) was higher than that in noncancerous tissues (29.19%) (OR = 9.45, 95% CI = (5.39, 16.59), p < 0.00001) (Fig 3A).