CKD-MBD = chronic kidney disease-mineral and bone disorder; 25(OH)D = 25-hydroxyvitamin D; 1,25(OH)2D = 1,25-dihydroxyvitamin D; 24,25(OH)2D3 = 24,25-dihydroxyvitamin D3; iPTH = intact parathyroid hormone; FGF23 = fibroblast growth factor 23. The gene discussed is FGF23; the disease is Marchiafava-Bignami disease.