MITF and melanoma: MITF has an important role in melanoma initiation and development due to its oncogenic function specifically for the melanocytes.40 MITF drives the progression of melanomas harboring BRAFV600E mutation by promoting melanocytes to synthesize the melanin to retain melanoma and activating the overexpression of antiapoptotic genes for survival.41 Therefore, MITF is a potential novel therapeutic target for malignant melanoma, and miR-26a may exert its antimelanoma effects by targeting MITF.