MITF and cancer: Several genes have been identified and validated to be the targets of miR-26a in multiple cancers including melanoma.12,13,39 Reuland et al. 13 reported that the expression of miR-26a is significantly downregulated in melanomas compared with melanocytes and miR-26a mediates apoptosis in melanoma by targeting the SODD in a few sensitive cell lines of melanoma.13 This study reports that MITF is a bona fide target of miR-26a.