Our real-time PCR analysis indicated that in colon cancer patients, Exo70 mRNA was significantly increased in 84.6% (11/13) tumor tissues compared with the matched non-tumor tissues (2.20 ± 1.05 versus 0.63 ± 0.56; P = 0.019; Fig. 1a). This evidence concerns the gene EXOC7 and malignant colon neoplasm.