To explore whether such situation also exists in colon cancer, we induced EMT with TGF-β in several colon cancer cells including HCT-116, SW620 and RKO and observed the mRNA changes of Exo70 isoform 1, 2 (M form in breast cancers), 4 and 5 (E form in breast cancers). This evidence concerns the gene TGFB1 and breast cancer.