LOX melanoma cells do not endogenously express CXCL16, nor CXCR6, and so, we generated LOX clones expressing transmembrane CXCL16 (LOX-CXCL16) or a C–terminally truncated version of transmembrane CXCL16 (LOX-ΔCXCL16) and a clone from the empty expression vector (LOX-pcDNA) [13]. The gene discussed is CXCR6; the disease is melanoma.