EGR1 and Zika virus infectious disease: Several prosurvival genes are induced during ZIKV infection of hBMECs, including EGR1, ATF3, and BIRC3 (52, 53), and the constitutively induced chemokine CCL5 (40- to 2,327-fold 1 to 9 dpi) is also associated with cell survival (69, –, 72).