LRRK2 and Parkinson disease: Our results thus show that LRRK2 works as a dual regulator of WNT/β-catenin and WNT/PCP signaling (as PRICKLE1 and ILK), and suggest a possible additional role of LRRK2 in controlling biological processes regulated by the WNT/PCP pathway and deregulated in PD, such as axon-dendritic polarity and synaptic function.