We compared the protein and RNA expression of the 63 DEPs between African-American and Caucasian-American prostate cancer specimens; only caveolin-1, beta-catenin, myosin heavy chain-9, serine/arginine-rich splicing factor 1/splicing factor 2, double-stranded RNA-specific adenosine deaminase, and X-ray repair cross-complementing protein 5 had both protein and RNA data. The gene discussed is XRCC5; the disease is Familial prostate cancer.