Whilst the overall positivity rate of mutated ALK in NSCLC is published as being between 2 and 7 percent, the response rate to the ALK inhibitor Crizotinib was described as 57%, with a remarkably high rate of progression-free survival of 72% after 6 months of ALK-inhibitor therapy [17,24]. Here, ALK is linked to non-small cell lung carcinoma.