However, two groups of patients demonstrated a significant difference in STAT3 expression in NK cells: MFI results were 5070 ± 2951 in lung cancer patients (n = 10) versus 827 ± 614 in patients with gastric, sigmoid, and colon cancer (n = 4) (P = 0.016) (Fig. 5). This evidence concerns the gene STAT3 and colonic neoplasm.